Abstract

RECENT REPORTS including those of double-blind studies concerning the efficacy of gastric freezing as treatment of patients with medically refractory duodenal ulcers are conflicting. The reports of Rose 1 and S. L. Wangensteen 2 and their respective colleagues suggest that freezing produces relief from ulcer pain in most of such patients while the report of Perry and associates 3 indicates that freezing produces relief from ulcer pain in few of such patients. S. L. Wangensteen 2 states that gastric acid secretion is depressed for six months after freezing while the others 1,3 state that no change in acid secretion occurs thereafter. The reports of descriptive (qualitative) microscopical changes after gastric freezing are also conflicting. The report of Allcock and co-authors 4 suggests that the numbers of chief and parietal cells are temporarily decreased after freezing while the reports of Owens, 5 Nabseth, 6 and Gilat 7 and their respective co-workers

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