Abstract
IntroductionSeverely bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Healthcare resource use and costs are likely to be substantial but have not been fully quantified. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions.MethodsIn collaboration with the Trauma Audit Research Network (TARN) detailed patient-level data on in-hospital resource use, extended care at hospital discharge, and readmissions up to 12 months post-injury were collected on 441 consecutive adult major trauma patients with severe bleeding presenting at 22 hospitals (21 in England and one in Wales). Resource use data were costed using national unit costs and mean costs estimated for the cohort and for clinically relevant subgroups. Using nationally available data on trauma presentations in England, patient-level cost estimates were up-scaled to a national level.ResultsThe mean (95 % confidence interval) total cost of initial hospital inpatient care was £19,770 (£18,177 to £21,364) per patient, of which 62 % was attributable to ventilation, intensive care, and ward stays, 16 % to surgery, and 12 % to blood component transfusion. Nursing home and rehabilitation unit care and re-admissions to hospital increased the cost to £20,591 (£18,924 to £22,257). Costs were significantly higher for more severely injured trauma patients (Injury Severity Score ≥15) and those with blunt injuries. Cost estimates for England were £148,300,000, with over a third of this cost attributable to patients aged 65 years and over.ConclusionsSeverely bleeding major trauma patients are a high cost subgroup of all major trauma patients, and the cost burden is projected to rise further as a consequence of an aging population and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios. The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/or treatment practice can begin to be evaluated. Further studies are still required to determine the full costs of post-discharge care requirements, which are also likely to be substantial.Electronic supplementary materialThe online version of this article (doi:10.1186/s13054-015-0987-5) contains supplementary material, which is available to authorized users.
Highlights
Bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths
Severely bleeding major trauma patients are a small yet high cost subgroup of all major trauma patients, and costs are projected to rise further as a consequence of an aging population, and as evidence continues to emerge on the benefits of early and simultaneous administration of blood products in pre-specified ratios
The findings from this study provide a previously unreported baseline from which the potential impact of changes to service provision and/or treatment practice can begin to be evaluated
Summary
Bleeding trauma patients are a small proportion of the major trauma population but account for 40 % of all trauma deaths. Knowledge of costs is essential for developing targeted cost reduction strategies, informing health policy, and ensuring the cost-effectiveness of interventions. Campbell et al Critical Care (2015) 19:276 the National Health Service (NHS) of treating severe bleeding in trauma has yet to be fully quantified [9,10,11]. For health service managers, understanding the key cost drivers can help with the development of targeted cost reduction strategies. For health economists, such data can be used as inputs into studies evaluating the costeffectiveness of new bleeding cessation interventions [12]. The nation-wide cost burden of severe bleeding in trauma can be compared with that of other conditions, and potential future costs, such as those resulting from an aging population, can be modelled
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