Abstract

BackgroundThe winter pressure often experienced by NHS hospitals in England is considerably contributed to by severe cases of seasonal influenza resulting in hospitalisation. The prevention planning and commissioning of the influenza vaccination programme in the UK does not always involve those who control the hospital budget. The objective of this study was to describe the direct medical costs of secondary care influenza-related hospital admissions across different age groups in England during two consecutive influenza seasons.MethodsThe number of hospital admissions, length of stay, and associated costs were quantified as well as determining the primary costs of influenza-related hospitalisations. Data were extracted from the Hospital Episode Statistics (HES) database between September 2017 to March 2018 and September 2018 to March 2019 in order to incorporate the annual influenza seasons. The use of international classification of disease (ICD)-10 codes were used to identify relevant influenza hospitalisations. Healthcare Resource Group (HRG) codes were used to determine the costs of influenza-related hospitalisations.ResultsDuring the 2017/18 and 2018/19 seasons there were 46,215 and 39,670 influenza-related hospital admissions respectively. This resulted in a hospital cost of £128,153,810 and £99,565,310 across both seasons. Results showed that those in the 65+ year group were associated with the highest hospitalisation costs and proportion of in-hospital deaths. In both influenza seasons, the HRG code WJ06 (Sepsis without Interventions) was found to be associated with the longest average length of stay and cost per admission, whereas PD14 (Paediatric Lower Respiratory Tract Disorders without Acute Bronchiolitis) had the shortest length of stay.ConclusionThis study has shown that influenza-related hospital admissions had a considerable impact on the secondary healthcare system during the 2017/18 and 2018/19 influenza seasons, before taking into account its impact on primary health care.

Highlights

  • The winter pressure often experienced by NHS hospitals in England is considerably contributed to by severe cases of seasonal influenza resulting in hospitalisation

  • The seasonal influenza data were stratified by the following age groups: < 65, 65–74 and 75+ years in order to assess the burden of illness in both the under 65 s and the elderly

  • Influenza-related hospitalisations In the 2017/18 influenza season, 46,215 influenza-related hospital admissions were recorded for 41,730 individual patients in England

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Summary

Introduction

The winter pressure often experienced by NHS hospitals in England is considerably contributed to by severe cases of seasonal influenza resulting in hospitalisation. The objective of this study was to describe the direct medical costs of secondary care influenza-related hospital admissions across different age groups in England during two consecutive influenza seasons. Seasonal influenza disease epidemics contribute considerably to winter pressures in the UK with severe cases resulting in hospitalisation due to complications. Laboratory confirmed influenza was associated with a total of 3175 admissions to intensive care unit/high dependency unit in England [4]. A 2016 study by Matias et al [5] estimated the burden of influenza in the UK using weekly hospital admission and death data in combination with Public Health England’s virology reports on influenza and respiratory syncytial virus. Evidence suggests prevention and early intervention may be effective mechanisms for reducing the burden of influenza

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