Abstract
NIHR Cardiovascular Biomedical Research Unit, Royal Brompton & Harefield NHS Foundation Trust and Imperial College London, London, UK Full list of author information is available at the end of the article Figure 1 Representative short-axis images from subjects scanned for RV T1 mapping by fat-water separated, MSPrep dark blood imaging. Images for five subjects with repaired tetralogy of Fallot and five healthy volunteers shown (one subject per column): Top row MoCo averaged water-only image at Ts 600 ms, Second row MoCo averaged water-only anchor image at same window/level, Third row MoCo averaged fat only image, Bottom row T1 map generated from registration and 2-parameter fit of the six images per sampling scheme. Heng et al. Journal of Cardiovascular Magnetic Resonance 2016, 18(Suppl 1):O26 http://www.jcmr-online.com/content/18/S1/O26
Highlights
There are clear clinical drivers for right ventricular (RV) T1 mapping in patients with repaired tetralogy of Fallot, in whom myocardial fibrosis is implicated in adverse clinical outcomes
RV T1 maps were obtained in all subjects, with interobserver reproducibility of native RV myocardial T1 (CoV 1.8%) and RV ECV (CoV 6.8%)
There was no significant difference in RV native T1 and ECV of patients with repaired tetralogy of Fallot (rTOF) compared to the controls who had thin RV wallls (Figure 2)
Summary
There are clear clinical drivers for right ventricular (RV) T1 mapping in patients with repaired tetralogy of Fallot (rTOF), in whom myocardial fibrosis is implicated in adverse clinical outcomes. Considerable technical challenges exist, due to thin mobile RV wall with
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