Quantifying Asymmetry in Gait: The Weighted Universal Symmetry Index to Evaluate 3D Ground Reaction Forces.

Sónia A Alves,Alison N Agres,Alwina Bender,Georg N Duda,Rainald M Ehrig,Peter C Raffalt

doi:10.3389/fbioe.2020.579511

Abstract

Though gait asymmetry is used as a metric of functional recovery in clinical rehabilitation, there is no consensus on an ideal method for its evaluation. Various methods have been proposed to analyze single bilateral signals but are limited in scope, as they can often use only positive signals or discrete values extracted from time-scale data as input. By defining five symmetry axioms, a framework for benchmarking existing methods was established and a new method was described here for the first time: the weighted universal symmetry index (wUSI), which overcomes limitations of other methods. Both existing methods and the wUSI were mathematically compared to each other and in respect to their ability to fulfill the proposed symmetry axioms. Eligible methods that fulfilled these axioms were then applied using both discrete and continuous approaches to ground reaction force (GRF) data collected from healthy gait, both with and without artificially induced asymmetry using a single instrumented elbow crutch. The wUSI with a continuous approach was the only symmetry method capable of identifying GRF asymmetry differences in different walking conditions in all three planes of motion. When used with a continuous approach, the wUSI method was able to detect asymmetries while avoiding artificial inflation, a common problem reported in other methods. In conclusion, the wUSI is proposed as a universal method to quantify three-dimensional GRF asymmetries, which may also be expanded to other biomechanical signals.

Highlights

Unilateral lower limb injuries and degenerative musculoskeletal diseases often lead to asymmetries in applied loads during movement (McCrory et al, 2001; Shakoor et al, 2011; Queen et al, 2015)
Hereby we presented a novel method—the weighted universal symmetry index—that allows to quantify gait asymmetry in a manner that both overcomes limitations identified in previous methods and fulfills the above defined symmetry axioms
The established symmetry axioms allowed for the definition of a robust and efficient symmetry method and enabled an evaluation against existing methods and a newly proposed weighted Universal Symmetry Index, weighted universal symmetry index (wUSI), method

Summary

Introduction

Unilateral lower limb injuries and degenerative musculoskeletal diseases often lead to asymmetries in applied loads during movement (McCrory et al, 2001; Shakoor et al, 2011; Queen et al, 2015). Gait asymmetry is used as a metric to evaluate pathology status, as longitudinal measurements give insight into patients’ functional recovery or disease progression (Aqil et al, 2016; Wesseling et al, 2018). Such assessments of gait asymmetry can be used to evaluate and compare different interventions that target the underlying disease (Bohm et al, 2016) and are frequently linked to patients’ clinical outcomes (Farkas et al, 2019). Rehabilitation programs lack precise guidance, as there is no consensus on how to effectively quantify such asymmetries (Lauziere et al, 2014; Viteckova et al, 2018)

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Conclusion