Abstract
The proliferation of substandard drugs is a major public health challenge, especially in developing countries which lacks adequate resources to effectively monitor their prevalence. Currently, there are no reliable statistics on the level of incidence of fake drugs in Nigeria. The quality of medicines is an integral part in ensuring that pharmaceutical products are fit for their intended use, comply with requirements of marketing authorization and do not expose consumers to risks. For this to be achieved, there must be a system of quality assurance, which incorporates aspects including product development, manufacturing, distribution, and storage. This study aimed at quantifying the content of ten (10) brands of metronidazole infusion marketed in Abuja by UV-Spectroscopic method. Ten (10) brands of metronidazole were purchased in different pharmacies within the city of Abuja and were assayed using UV-Spectroscopic method as stated in British Pharmacopoeia 2017 edition. All the ten (10) brands of metronidazole that were assayed had a percentage content of 100.97% to 108.15%. From the study carried out, all the brands of metronidazole infusion complied with the content uniformity test as stated in the British Pharmacopeia.
Highlights
Cassava (ManihotesculentaCrantz) is a woody shrub native to South America [1]
Cassava samples were collected from five Woredas of Jimma zone; Mana with altitude of (1786 m), Sakachekorsa (2107 m), Dedo (2096 m), Sokoru (1620 m), Gomma (1805 m), above sea level were selected purposively and representative samples were obtained randomly
Cassava tuber has a major potential as a substitute for other types of flour or it can be used by mixing it with other flours
Summary
Cassava (ManihotesculentaCrantz) is a woody shrub native to South America [1]. The plant is known by its edible starchy tuberous root. It is a drought tolerant, staple food crop grown in tropical and subtropical areas where many people are afflicted to under nutrition, making it a potentially valuable food for developing countries [1]. It is widely used in food security because; its mature edible tuber can be stored in the ground for up to three years. Because of its capability in producing efficient food energy, availability throughout the year, tolerance to extreme stress conditions, and suitability to present farming and food systems in Africa, cassava plays a role to alleviate the African food crisis [2]
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