Quantification of septal and whole slice myocardial blood flow by myocardial perfusion CMR is similar in healthy volunteers

Bara Erhayiem,Adam K Mcdiarmid,David P Ripley,Ananth Kidambi,John P Greenwood,Steven Sourbron,Sven Plein

doi:10.1186/1532-429x-16-s1-p12

Abstract

Background First pass myocardial perfusion CMR allows quantification of myocardial blood flow (MBF). MBF estimation with whole-heart tissue response may be useful in a variety of systemic diseases, but can be limited by suboptimal imaging in one or more segments. The interventricular septum (IVS) offers an attractive target for MBF imaging, as it offers higher signal and less partial volume artefact from blood pool. It has been proposed that T1 measurements taken from the IVS are more reliable than measurements from an entire short axis slice. We hypothesised that MBF estimation from the IVS would be similar to whole-heart estimation.

Highlights

First pass myocardial perfusion CMR allows quantification of myocardial blood flow (MBF)
Quantification of septal and whole slice myocardial blood flow by myocardial perfusion CMR is similar in healthy volunteers
MBF estimation with whole-heart tissue response may be useful in a variety of systemic diseases, but can be limited by suboptimal imaging in one or more segments

Summary

Introduction

First pass myocardial perfusion CMR allows quantification of myocardial blood flow (MBF). Quantification of septal and whole slice myocardial blood flow by myocardial perfusion CMR is similar in healthy volunteers Background First pass myocardial perfusion CMR allows quantification of myocardial blood flow (MBF). MBF estimation with whole-heart tissue response may be useful in a variety of systemic diseases, but can be limited by suboptimal imaging in one or more segments.

Results

Conclusion