Abstract
We developed a sensitive and selective method for quantifying nitrate, thiocyanate, perchlorate and iodide in human urine using ion chromatography coupled with electrospray ionization tandem mass spectrometry. Analysis of proficiency testing materials and spiked urine indicates that the method is precise (coefficients of variation <5%) and accurate (relative percent differences <7.9%). Analytical response was linear across the physiologically relevant concentration range for the analytes, and adequately sensitive to quantify the analytes in >99% of urine samples tested. Measurement of these four toxicologically-related analytes in one assay will provide useful information for assessing potential linkage between exposure and health effects.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
