Abstract

Quantification of coronary vessel wall thickness using a flexible time-resolved golden angle dual-inversion recovery acquisition for facilitated sequence timing at 3T

Highlights

  • Positive vessel wall remodeling is an early marker of coronary artery diseases

  • Data acquisition was performed at 3T (Prisma, Siemens), in 15 healthy volunteers, with both a conventional radial double inversion recovery (DIR) and a version of it which exploits the golden angle radial trajectory and a prolonged acquisition window (Fig 1)

  • The quantified vessel wall thickness remained unchanged among the two reconstructions (0.95 ± 0.27 for the baseline, and 0.97 ± 0.18 for the best frame, p = NS)

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Summary

Introduction

Positive vessel wall remodeling is an early marker of coronary artery diseases. Its early detection could improve prognosis of adverse cardiovascular events. Methods Data acquisition was performed at 3T (Prisma, Siemens), in 15 healthy volunteers, with both a conventional radial DIR (baseline) and a version of it which exploits the golden angle radial trajectory and a prolonged acquisition window (Fig 1). Relevant imaging parameters were: flip-angle 16°, FOV 260 mm[2], TE 3.2 ms, TR 6.5 ms, slice thickness 8 mm, spatial resolution 0.6 mm[2].

Results
Conclusion

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