Abstract
Abstract : The primary objectives of this research were to determine the capabilities of ESI-IMS for monitoring of aqueous samples containing chemical warfare agents or their subsequent degradation products. Rapid analysis times, excellent sensitivity, and potential portability make IMS an excellent tool for field applications. The ion chemistry for several chemical warfare degradation products were studied both with a prototype instrument and a high-resolution ESI-IMS instrument coupled with a quadrupole mass spectrometer (MS), showing excellent sensitivities for these compounds. Also, the ability to directly monitor water samples without prior sample preparation was shown. A portable ESI-IMS instrument has been designed and constructed. A high resolution ESI-IMS instrument coupled with a time of flight MS was assembled and showed excellent sensitivities for several chemical warfare degradation compounds. Due to the time compatibility of IMS and TOFMS, nine compounds were all resolved in two dimensions (mobility and m/z) within a minute.
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