Quality of Life in Psoriasis Patients and Its Correlation with Disease Severity

,Jamile Abed,Shatila Torabi,Fakhrozaman Pezeshkpoor,Naghmeh Zabolinejad,Faezeh Golnouri

doi:10.30699/jambs.26.119.1

Abstract

Background & Objective: Psoriasis is a chronic and relapsing disease with a prevalence of 2%. Since it is a chronic and non-fatal skin disease, its impact on quality of life in patients is underestimated compared to other diseases. This study points out to the importance of the quality of life in these patients and their correlation with disease severity. Materials & Methods: Quality of life of psoriasis patients was assessed by using the Dermatology Life Quality Index (DLQI) and psoriasis severity was measured, using Psoriasis Area Severity Index (PASI). DLQI were compared regarding age, gender and affected areas in patients. Results: Among 135 patients, 67 (49.6%) were male and 68 (50.4%) were female. The mean age of subjects was 41.49±15.43 years (ranging from 17 to 83 years). The mean DLQI score was 10.73±7.3 (ranging from 0 to 26). Independent t-test showed that the mean DLQI score was significantly greater in women than men (P=0.031) Spearman test showed positive correlation between DLQI and age as well as PASI and DLQI. Conclusion: Results of this study showed a positive and significant correlation between PASI score and quality of life of patients, which implies that with increasing the severity of the disease, the effect of psoriasis on patients' quality of life increases as well.

Highlights

Psoriasis is a chronic relapsing skin disease, characterized by scaly red plaques that are more likely to involve the scalp, knees, and elbows [1]
Independent t-test showed that the mean Dermatology Life Quality Index (DLQI) score was significantly greater in women than men (P=0.031)
Results of this study showed a positive and significant correlation between Psoriasis Area Severity Index (PASI) score and quality of life of patients, which implies that with increasing the severity of the disease, the effect of psoriasis on patients' quality of life increases as well

Summary

Introduction

Psoriasis is a chronic relapsing skin disease, characterized by scaly red plaques that are more likely to involve the scalp, knees, and elbows [1]. In a study by Zandi et al, there was a correlation between the quality of life and disease severity in psoriasis patients [13]. It seems that investigating the quality of life in psoriasis patients along with clinical severity of their disease can result in choosing the best type of treatment for these patients This helps increase the satisfaction level of their treatment. The aim of this study was to evaluate the quality of life of psoriasis patients and its correlation with disease severity in Iran. Psoriasis is a chronic and relapsing disease with a prevalence of 2% Since it is a chronic and non-fatal skin disease, its impact on quality of life in patients is underestimated compared to other diseases. This study points out the importance of the quality of life in these patients and their correlation with disease severity

Objectives

Methods

Results

Conclusion