Abstract

Objective: To assess sociodemographic factors and cancer information on patients' quality of life with head and neck cancer . Material and Methods: This cross-sectional study was conducted on 69 patients with head and neck cancer who attended in one of the oncology centers in Mashhad, Iran, from September 2019 to December 2019. Data was collected through a questionnaire consisted of demographic information (gender, age, educational level, and job) and cancer information (type, location, treatment, clinical stage) and standard quality of life questionnaire (QLQ-H&N35). Data analyzed in SPSS22 software using T, ANOVA, Linear regression tests at 0.05 significant levels. Results: 49 participants (72.1%) were men. The mean age was 60.48 ± 13.74 years. Forty-nine participants (72.1%) had squamous cell carcinoma and 26 participants (38.2%) had a larynx tumor. Forty-six participants (67.6%) were in clinical stage 3, mainly with a problem and complain about hard food swallowing, xerostomia and speech. The mean score of QLQ-H&N35 was 42.06 ± 20.12 from 90. Quality of life in 47.1% of cases was moderate. There was no significant relationship between gender, job, educational level, type and location of cancer (p>0.05). There was a significant relationship between the patient's age, clinical stage, type of treatment, and quality of life (p<0.05) . Conclusion: Quality of life in 47.1% was moderate. Clinical stage, age of patients and type of treatment statically and significantly affected the quality of life. Assessing quality of life in HNC patients can identify important side effects of treatment that affected quality of life and look for ways to improve QoL.

Highlights

  • Skeletal Class III malocclusion is a condition in which early treatment is often advocated due to fact that in an early age, the skeletal responsivity to corrective orthopedic forces is good, leading to satisfactory results, especially in the short-term [1,2,3,4]

  • Some authors developed some orthopedic approaches, even with the use of miniscrews [710] and different expansive protocol to disarticulate maxillary jaw, making it more responsive to facemask forward protraction [11,12,13,14,15,16], in about 25% of the cases the Class III growth pattern returns [6] leading to unesthetic facial condition, poor occlusion, periodontal problems [17] and psychological problems such as low self-esteem, stress, anxiety, problems undermining the quality of life [18,19,20]

  • Orthognathic surgeries were performed by the same expert maxillo-facial surgeon (UB), and they comprised both Le Fort I maxillary osteotomy according to Bell [27] and bilateral sagittal split mandibular osteotomy (BSSO)

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Summary

Introduction

Some authors developed some orthopedic approaches, even with the use of miniscrews [710] and different expansive protocol to disarticulate maxillary jaw, making it more responsive to facemask forward protraction [11,12,13,14,15,16], in about 25% of the cases the Class III growth pattern returns [6] leading to unesthetic facial condition, poor occlusion, periodontal problems [17] and psychological problems such as low self-esteem, stress, anxiety, problems undermining the quality of life [18,19,20] In these cases, the surgical bimaxillary orthognathic approach becomes the only possibility to solve severe Class III malocclusions with good facial aesthetics, especially in cases characterized by a high-angle, skeletal open-bite, skeletal asymmetry and thin periodontal biotype. These methods are effective, they have some limitations, especially when complex cases with severe dento-facial deformities are present [22]

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