Abstract
Quality of life (QOL) and psychosocial functioning of children diminishes with the onset of seizures. The adult outcomes of patients show some improvements with good seizure control but impairments in some areas remain. Epilepsy surgery in childhood has the potential to eliminate seizures, which may lead to improvements in QOL and psychosocial functioning. This chapter reviews recent work on the long-term QOL and psychosocial outcomes following epilepsy surgery in childhood. The few studies that have examined these outcomes find overall improvements in QOL, but are not always concordant as to which QOL domains show improvements. Similarly, although improvements are found in overall psychosocial functioning, there is no consensus on which domains improve. Improvements in QOL and psychosocial functioning, when evident, are consistently associated with seizure freedom. More recently, mood and affective symptoms have been found to be integral in ratings of QOL. Further work is needed to identify specific affective symptoms that lead to diminished QOL and psychosocial functioning and to identify other variables that may be involved, such as IQ or memory, and family function.
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