Abstract
Objective: Alcohol use disorder (AUD) is a serious issue worldwide and frequently co-occurs with depression. However, the quality of life (QOL) of AUD patients with and without depression is not well studied in the Chinese Han population. The aim of this study was to investigate QOL and its correlates in AUD patients with and without depression in China.Methods: Five hundred and fifteen psychiatric patients diagnosed with AUD were recruited. All these patients completed the Beck Depression Inventory (BDI) to assess depression, the Medical Outcome Study 36-Item Short Form Health Survey (SF-36) to evaluate QOL and the Alcohol Use Disorders Identification Test (AUDIT) to measure the severity of drinking.Results: Compared with AUD patients without depression, those with depression had a lower QOL in all eight domains of the SF-36 (all P < 0.001), but were more willing to have alcohol-related treatment (P < 0.05). Negative correlations were noted between (i) the BDI total score and all eight domains of the SF-36 (all P < 0.001); and (ii) between the AUDIT total score and six domains of the SF-36 (all P < 0.05).Conclusions: Depression impairs QOL in patients with AUD in China. Early intervention in comorbid depression to improve QOL is needed.
Highlights
Alcohol use disorder (AUD) is a severe public health and medical issue in China
We found that depressed AUD patients had a lower quality of life (QOL) in all eight domains of the SF-36 and were more willing to take alcohol-related treatment than non-depressed AUD patients
We observed that the Beck Depression Inventory (BDI) total score were negatively correlated with all eight domains of the SF-36 and the Alcohol Use Disorders Identification Test (AUDIT) total score were negatively correlated with six domains of the SF-36
Summary
Alcohol use disorder (AUD) is a severe public health and medical issue in China. AUD has caused enormous medical, social and economic burdens and costs in China, Quality of Life in Alcohol Use Disorder the treatment rate for AUD is dramatically low [2]. Many studies found that AUD patients reported poorer QOL compared with the general population [3,4,5,6,7], in the emotional [8,9,10,11,12], mental health [13, 14] and social functioning domains [11]. Studies have reported that alcohol abstinence and its maintenance could improve QOL in AUD patients [8, 20,21,22,23]
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