Quality of life and influencing factors of functional dyspepsia in different subtypes

Abstract

Objective To investigate the quality of life and influencing factors of functional dyspepsia(FD) in different subtypes. Methods Two hundred and ten patients with FD were divided into postprandial distress syndrome(PDS) , epigastric pain syndrome (EPS) and overlapping(PDS+ EPS). SF-36 quality of life questionnaire(SF-36), Hamilton depression scale(HAMD), Hamilton anxiety scale(HAMA), the Eysenck’s Personality Questionnaire(EPQ) and the life event scale (LES) were used in the three groups. Results ①There was no significant difference in physiological function(PF)or role physical (RP)among the three groups; the body pain(BP), general health(GH), vitality(VT), social function(SF), role Emotional(RE), mental health(MH), physical component summary(PCS)and mental component summary(MCS) in patients with PDS+ EPS were lower than those of patients with PDS or EPS. The VT and MH, PDS were higher than those of EPS. There was no significant difference among the rest of the dimension between PDS and EPS. ②PCS and MCS in three subtypes, the influencing factors were Somatic anxiety factor. In the PCS, the influencing factor was PDS with sleep disturbance factor. In the MCS, the influencing factors were PDS with Sleep disturbance factor and L, EPS with sleep disturbance factor and E, PDS + EPS with N. Conclusions There are significant differences in the quality of life among the three subtypes of FD patients. Different psychological intervention and treatment should be taken according to different subtypes of patients, in order to cure disease and improve their quality of lives. Key words: Functional dyspepsia; Subtypes; Quality of life; Influencing factors