Abstract
This study was aimed to compare serial long-term postoperative changes in quality-of-life (QoL) between photoselective-vaporization (PVP) using 120W-High-Performance-System and holmium-laser-enucleation (HoLEP) in benign-prostatic-hyperplasia (BPH) patients and to identify factors influencing the QoL improvement at the short-term, mid-term and long-term follow-up visits after surgery. We analyzed 1,193 patients with a baseline QoL-index ≥2 who underwent PVP (n = 439) or HoLEP (n = 754). Surgical outcomes were serially compared between the two groups at up to 60-months using the International-Prostatic-Symptom-Score (I-PSS), uroflowmetry, and serum PSA. We used logistic regression analysis to identify predictors of QoL improvement (a reduction in the QoL-index ≥50% compared with baseline) at the short-term (12-months), mid-term (36-months), and long term (60-months) follow-up after surgery. In both groups, the QoL-index was decreased throughout the entire follow-up period compared with that at baseline. There were no significant differences in postoperative changes from the baseline QoL-index between the two groups during the 48-month follow-up, except at 60-months. The degree of improvement in QoL at 60-months after HoLEP was greater than that after PVP. A lower baseline storage-symptom-subscore and a higher bladder-outlet-obstruction-index (BOOI) were independent factors influencing QoL improvement at the short-term. No independent factor influences QoL improvement at the mid- or long-term.
Highlights
This study was aimed to compare serial long-term postoperative changes in quality-of-life (QoL) between photoselective-vaporization (PVP) using 120W-High-Performance-System and holmiumlaser-enucleation (HoLEP) in benign-prostatic-hyperplasia (BPH) patients and to identify factors influencing the QoL improvement at the short-term, mid-term and long-term follow-up visits after surgery
In comparing the baseline characteristics between the PVP and holmium laser enucleation of the prostate (HoLEP) groups, the PVP group had a higher level of serum PSA, a smaller prostate volume, a higher voiding symptom score (VSS), a higher storage symptom score (SSS), a higher total International Prostate Symptom Score (I-PSS), a longer operation time, and greater energy applied during the surgeries than the HoLEP group (Table 1)
Serial postoperative outcomes after PVP or HoLEP. In both the PVP and HoLEP groups, the value of the QoL index at each follow-up visit was significantly decreased during the entire follow-up period after surgery compared with that at the baseline (Fig. 1)
Summary
This study was aimed to compare serial long-term postoperative changes in quality-of-life (QoL) between photoselective-vaporization (PVP) using 120W-High-Performance-System and holmiumlaser-enucleation (HoLEP) in benign-prostatic-hyperplasia (BPH) patients and to identify factors influencing the QoL improvement at the short-term, mid-term and long-term follow-up visits after surgery. We used logistic regression analysis to identify predictors of QoL improvement (a reduction in the QoLindex ≥50% compared with baseline) at the short-term (12-months), mid-term (36-months), and long term (60-months) follow-up after surgery. To the best of our knowledge, few studies have directly compared postoperative treatment outcomes between PVP and HoLEP, focusing on improvement in QoL during a serial long-term follow-up period, a few short-term follow-up studies showed no significant differences in the postoperative improvement of QoL during a one-year follow-up after surgery[14,15]. The asterisk (*) indicates a statistically significant difference (Independent t-test or Chi-squared test, p < 0.05)
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
