Abstract
ObjectiveComprehensive analysis and comparison of HRQoL following different bariatric interventions through systematic review with network meta-analysis.BackgroundDifferent types of bariatric surgeries have been developed throughout the years. Apart from weight loss and comorbidities remission, improvement of health-related quality of life (HRQoL) is an important outcome of metabolic surgery.MethodsMEDLINE, EMBASE, and Scopus databases have been searched up to April 2020. Inclusion criteria to the analysis were (1) study with at least 2 arms comparing bariatric surgeries; (2) reporting of HRQoL with a validated tool; (3) follow-up period of 1, 2, 3, or 5 years. Network meta-analysis was conducted using Bayesian statistics. The primary outcome was HRQoL.ResultsForty-seven studies were included in the analysis involving 26,629 patients and 11 different surgeries such as sleeve gastrectomy (LSG), gastric bypass (LRYGB), one anastomosis gastric bypass (OAGB), and other. At 1 year, there was significant difference in HRQoL in favor of LSG, LRYGB, and OAG compared with lifestyle intervention (SMD: 0.44; 95% CrI 0.2 to 0.68 for LSG, SMD: 0.56; 95% CrI 0.31 to 0.8 for LRYGB; and SMD: 0.43; 95% CrI 0.06 to 0.8 for OAGB). At 5 years, LSG, LRYGB, and OAGB showed better HRQoL compared to control (SMD: 0.92; 95% CrI 0.58 to 1.26, SMD: 1.27; 95% CrI 0.94 to 1.61, and SMD: 1.01; 95% CrI 0.63 to 1.4, respectively).ConclusionsLSG and LRYGB may lead to better HRQoL across most follow-up time points. Long-term analysis shows that bariatric intervention results in better HRQoL than non-surgical interventions.Graphical abstract
Highlights
Depression, anxiety, and low self-esteem can be significant psychological consequences of obesity [1]
LSG and LRYGB may lead to better Health-Related Quality of Life (HRQoL) across most follow-up time points
Long-term analysis shows that bariatric intervention results in better HRQoL than non-surgical interventions
Summary
Depression, anxiety, and low self-esteem can be significant psychological consequences of obesity [1]. Both physical and psychological consequences can be debilitating and decrease overall Health-Related Quality of Life (HRQoL). Bariatric surgery causes significant changes in patients’ life, including HRQoL. There is a growing body of literature demonstrating an improvement of both the physical and psychological status of the patients following bariatric procedures [2]
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