Abstract
BackgroundAccording to market investigation, two kinds of Polygoni Multiflori Radix decoction pieces with different specifications are commercially available: irregular thick slices (0.7-1.3 cm) and length-wise into thin slices (0.11-0.2 cm). The objective of this study was to evaluate the quality of various samples of Polygoni Multiflori Radix decoction pieces and its dregs.ResultsA simple and reliable high performance liquid chromatographic method was developed for determination the contents of 2,3,5,4′-tetrahydroxystilbene-2-O-β-D- glucopyranoside (THSG), emodin and physcion, which were considered to be potent active ingredients. The results showed that the contents of THSG, emodin and physcion varied in samples of different diameters and thicknesses. The results also indicated the dregs of Polygoni Multiflori Radix still contained a considerable amount of THSG, emodin and physcion.ConclusionThe various commercial specifications of Polygoni Multiflori Radix sold in the markets did not correlate with their prices, and the dregs of Polygoni Multiflori Radix can be further utilized.
Highlights
According to market investigation, two kinds of Polygoni Multiflori Radix decoction pieces with different specifications are commercially available: irregular thick slices (0.7-1.3 cm) and length-wise into thin slices (0.11-0.2 cm)
The results showed that methanol extraction produced the best yield for tetrahydroxystilbene-2-O-β-D- glucopyranoside (THSG), emodin and physcion
The results indicated there was no significant difference of the contents of THSG, emodin and physcion occurred between 120 min and 180 min extraction time
Summary
Two kinds of Polygoni Multiflori Radix decoction pieces with different specifications are commercially available: irregular thick slices (0.7-1.3 cm) and length-wise into thin slices (0.11-0.2 cm). The objective of this study was to evaluate the quality of various samples of Polygoni Multiflori Radix decoction pieces and its dregs. Two kinds of decoction pieces of Polygoni Multiflori Radix are recorded in the Chinese Pharmacopoeia: raw and processed [1]. The raw material of Polygoni Multiflori Radix is often processed with black soybean juice or directly steamed until it is brown on all sides; it is cut into slices, which are sold as “processed” decoction pieces. In the practice of traditional Chinese medicine, raw Polygoni Multiflori Radix is used to counteract toxicity, cure carbuncles, and relax the bowels, while processed decoction pieces are used for replenishing the liver and kidney with vital essence and blood, blackening the hair and strengthening the tendons and bones [1].
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