Abstract
The Saussureae radix has been used for treatment of abdominal pain, vomiting, diarrhea, chronic inflammation, and antibacterial effect. The quality of these herbs has been affected by many factors such as collection time, place, temperature, cultivation environment and manufacturing process. Costunolide, dihydrocostunolide, costuslactone, dihydrocostuslactone, α-costol, saussurea lactone, and costuslactone are main active components in Saussureae radix according to the literature. We used costunolide and dihydrocostunolide as marker compounds for quality evaluation. 38 samples of Saussureae were collected from those habitats in Korea and China. The developed HPLC-DAD method was applied to investigate for quality control of Saussureae radix sample. The content of costunolide varied from 0.674% to1.812% and for dihydrocostunolide, the content varied from 1.310% to 3.035%. The all samples showed similar pattern.
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