Abstract

Chronic pancreatitis (CP) is characterized by a long-term evolution over 10–20 years or more. Morphologically, CP is a progressive process, leading finally to “cirrhosis” of the pancreas combined with pancreatic dysfunction. The clinical spectrum of CP varies in relation to (a) duration of the disease, (b) progressive pancreatic dysfunction, and (c) the presence of local complications. Three typical clinical patterns can be distinguished: 1. Uncomplicated CP, early stage (e.g., recurrent short episodes of “acute” pancreatitis) 2. Uncomplicated CP, late stage (e.g., lack of pain, diarrhea, steatorrhea, diabetes) 3. Complicated CP, often associated with persistent severe pain, pseudocysts, obstructive jaundice, etc.

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