Abstract

Introduction: Plants and their constituent are having potential of treating any human suffering in form of disease. Various combination of plant extract is used as a remedy for treating these disorders. However the usage and dose of these extract which are in random and unspecified is a big challenge for acceptance as a medicine till not get standardized. The most important Ayurvedic drugs i.e. Saptavimsatika guggulu had been selected from Ayurvedic famous books named API Ayurvedic Monographs for Phytochemical and Physicochemical study. This Ayurvedic drugs is mainly and commonly used in the treatment of heart, skin and stomach related disease. Drug preparation was done during an event organized by our University under theme Rx-Thon.
 Methods: Physico and Phytochemical study both had been done in the labs of School of Pharmacy, Graphic Era Hill University. Values like Exractive value, Ash value, Mosture content, pH values, True density, bulk density, angle of repose, carr's index, hausner's ratio, Florescence analysis, TLC was covered in the study
 Result: Phytochemical study revealed that reducing sugars, tannin, phenolic compounds, saponin glycosides, and gum were present in the sample. Various physico-chemical parameter had been studied in the standardization procedures. The extractive, ash values, florescence analysis was done and was compared to reference standard.
 Conclusion: The physicochemical standardization of polyherbal formulation Saptavimsatika guggulu was carried out. The individual ingredients of the formulation were authenticated and standardized as per WHO guidelines and Indian Herbal Pharmacopoeia. The in-house formulation was prepared and studied for various physicochemical properties. Although no marketed sample is available hence a porbability is made under standard evaluation parameter to launch this product in market for sale.

Highlights

  • Standardization is the process of implementing and developing technical standards based on identifying inherent characteristics, constant parameters, and definitive qualitative and quantitative values which can produce assurance of quality, efficacy, safety, and reproducibility

  • Various physicochemical parameters had been studied in the standardization procedures and were compared with reference standards

  • No marketed sample is available; a probability is made under standard evaluation parameter to launch this product in market for sale

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Summary

Introduction

Standardization is the process of implementing and developing technical standards based on identifying inherent characteristics, constant parameters, and definitive qualitative and quantitative values which can produce assurance of quality, efficacy, safety, and reproducibility. It is the process of developing and approving on technical standards [1]. India can play the lead role in production of traditional formulation and can become major country for trade of these formulations This can be achieved only if the herbal products are evaluated and analyzed using sophisticated modern techniques of standardization [3]. Saptavimsatika Guggulu is a polyherbal ayurvedic classical formulation used in angina pectoris, cough, asthma, intercostal neuralgia inflammation, piles, fistula-in-ano, pelvic pain, pain in mouth, pain in anus, and calculus [5]

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