Quality assurance of bacterial incidents associated with blood transfusion

Abstract

Transfusion associated bacterial sepsis, TABS, may be caused by-donor bacteremia,-bacteria from the donors skin,-bacteria brought by one of the persons handling the donation or the blood product, from collection and components preparation to the actual transfusion,-or bacteria introduced by a defect in one of the disposables used. Quality Assurance relies on the Good Transfusion Practices of the French Blood Agency all along the transfusion chain from the donor to the recipient. Active involvement of personnel, standardisation and controls as well as improvement of technics particularly as regarding donor selection, skin disinfection technics and collection are required. The ultimate control is hemovigilance with proper identification and investigation of all cases of TABS even with mild symptoms. Centralisation of data in the Haemovigilance scheme is a further step toward a better understanding and improvement of blood products bacterial security.