Abstract

Objective: To investigate areas in need of quality improvement within the diagnostic process and antibiotic treatment of acute respiratory tract infections (RTIs) in Danish general practice by using quality indicators (QIs).Design and setting: During a 4-week period in winter 2017, a prospective registration of patients diagnosed with RTIs was conducted in general practice in two regions of Denmark.Subjects: Throughout the registration period each patient with symptoms of an RTI was registered. Information about age, symptoms and findings, duration of symptoms, the use and result of clinical tests, allergy towards penicillin, referral to secondary care and the antibiotic given were recorded.Main outcome measures: Values and acceptable ranges for QIs focusing on the diagnostic process, the decision to prescribe antibiotics and the choice of antibiotics for patients with RTIs.Results: Regarding the diagnostic process nearly all QIs for patients diagnosed with acute pharyngotonsillitis and pneumonia fell within the acceptable range. Contrarily, the diagnostic QIs for patients with acute otitis media and acute rhinosinusitis were outside the acceptable range. All indicators designed to measure overuse of antibiotics were outside the acceptable range and nearly all indicators assessing if patients were sufficiently treated fell within the acceptable range. QIs assessing use of the recommended type of antibiotic were only within the acceptable range for patients diagnosed with acute pharyngotonsillitis.Conclusion: The findings indicate an overuse of antibiotics for RTIs in Danish general practice. Especially management of acute rhinosinusitis and acute bronchitis should be targeted in future quality improvement projects.KEY POINTS:To improve antibiotic prescribing in general practice it is important to focus on both the diagnostic process and the prescribing patterns.The findings indicate an overuse of antibiotics for acute respiratory tract infections in Danish general practice.Especially the diagnostic process and antibiotic prescribing patterns for acute rhinosinusitis and acute bronchitis could benefit from future quality improvement interventions.

Highlights

  • Antimicrobial resistance (AMR) has reached alarming levels in many parts of the world and is considered to be one of the largest threats to global health [1]

  • The findings indicate an overuse of antibiotics for acute respiratory tract infections in Danish general practice

  • According to the diagnostic process most quality indicators (QIs) for patients with acute pharyngotonsillitis and pneumonia fell within the acceptable range

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Summary

Introduction

Antimicrobial resistance (AMR) has reached alarming levels in many parts of the world and is considered to be one of the largest threats to global health [1]. Reducing the unnecessary use of antibiotics is essential when facing AMR [2,3]. General practice is responsible for the majority of antibiotics prescribed to humans [4]. Antibiotic prescriptions are often issued to patients with acute respiratory tract infections (RTIs) even though the effect is small, if any [5,6]. Despite increasing awareness of AMR, antibiotic prescribing remains high in general practice [4]. When fighting the unnecessary use of antibiotics, insight into data about antibiotic prescribing in combination with physician education has proven to be effective [7]. Often information about the antibiotic prescribing patterns

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