Quality assessment and phytochemical analysis of Clerodendrum serratum roots

Abstract

Objectives: Clerodendrum serratum (L.) Moon. (Verbenaceae) commonly known as bharangi is an important medicinal plant growing in India having traditional value to treat pain, inflammation, rheumatism, respiratory disorders and fever. The aim of present study is to develop pharmacognostical, physicochemical and phytochemical parameters for quality assessment of Clerodendrum serratum roots (CSR). Methods: The roots of C. serratum were evaluated for pharmacognostical, physicochemical parameters such as ash values (total ash, acid insoluble ash and water soluble ash), extractive values (alcohol and water soluble), moisture content, crude fiber content and foaming index according to WHO guidelines on quality control methods for medicinal plant materials. The phytochemical analysis was performed using chemical tests, ultraviolet spectroscopy, thin layer chromatography and quantitative estimation of secondary phytoconstituents. Results: The pharmacognostical and physicochemical parameters evaluated for the roots were found in compliance with the Pharmacopoeial standards of crude drug. The qualitative and quantitative phytochemical analysis of methanolic extract of CSR showed presence of phenolics, flavonoids, saponins and carbohydrates. Conclusion: The present investigation will be helpful for the identification and quality control of CSR.