Abstract
A qualitative colorimetric test has been developed for the identification and differentiation of fludrocortisone acetate, triamcinolone, and triamcinolone acetonide in pharmaceutical formulations. The test is based on a newly discovered reaction for fluorinated steroids and depends upon the formation of an amber color from fludrocortisone acetate, a yellow chromogen from hydrolyzed triamcinolone, and a pink color from triamcinolone acetonide by reaction of phenol, hydroquinone, and the phosphoric-sulfuric acid mixture.
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