Abstract
BackgroundTo evaluate ocular biometric parameters in different subtypes of acute angle closure and compared to fellow eyes of AAC and PACS eyes.MethodsThis is a retrospective chart review study. A total of 167 eyes (96 patients) consisting of 71 AAC eyes, 71 fellow eyes of AAC, and 25 PACS eyes were recruited. All patients underwent ocular examination and biometry. The mechanism of AAC was confirmed by ultrasound biomicroscopy. We then subdivided AAC eyes into four subgroups: crowded-angle (CR), lens subluxation (LS) pupillary block (PB), and plateau iris syndrome (PL). Outcome variables included anterior chamber depth (ACD), lens thickness (LT), vitreal length (VL), axial length (AL), lens position and relative lens position (LP and RLP, respectively), and lens axial length factor (LAF).ResultsAmong the three groups, ACD was shallower in AAC eyes than fellow eyes of AAC and PACS eyes (p < 0.01 for both) and AAC eyes demonstrated a lesser LP and RLP. The LT, VL, AL, and LAF were not significantly different among the three groups. Among the four subgroups, LS displayed the most shallow ACD (p = 0.01). The lens position in PL was greater than in CR and LS (p < 0.05 and <0.01, respectively).ConclusionsAAC eyes had a more anterior lens position than fellow eyes and PACS eyes, though lens thickness did not differ among the groups. As such, an anterior lens position may offer more sensitive prognostication regarding future development of AAC compared to lens thickness.
Highlights
To evaluate ocular biometric parameters in different subtypes of acute angle closure and compared to fellow eyes of Acute angle-closure (AAC) and primary angleclosure suspect (PACS) eyes
There was a female preponderance in each group, there was no difference in gender distribution between the groups (p = 0.94)
There was no significant difference in anterior chamber depth (ACD) between fellow eyes of AAC and PACS eyes (p = 0.99) (Table 1)
Summary
To evaluate ocular biometric parameters in different subtypes of acute angle closure and compared to fellow eyes of AAC and PACS eyes. Several ocular biometric parameters have been identified for angle-closure development, such as small corneal diameter [2], small radius of the anterior and posterior corneal curvature [2], short axial length, shallow central and peripheral anterior chamber depth [3, 4], thick and anteriorly positioned lens [5–8], and a large lens axial length factor [9, 10]. Anterior segment optical coherence tomography visualizes the angle well, it generally cannot sufficiently image the ciliary body. This limitation precludes appreciation of a plateau iris ( if the cornea is edematous, thereby precluding gonioscopy)
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