Abstract
The herbal drug licorice root may be derived from the plant species Glycyrrhiza glabra L., Glycyrrhiza uralensis Fisch, and/or Glycyrrhiza inflata Bat. which are morphologically, chemically, pharma-cologically, and toxicologically similar. However, if an ingredient of a dietary supplement is identified as a certain species and labeled as such on the product, appropriate analytical methodologies are required to assure the authenticity. Using high-performance thin-layer chromatography (HPTLC), we were able to distinguish clearly between G. glabra and G. uralensis, the most commonly used species, which allowed us to check the corresponding label claims of twenty-six dietary supplements. Two samples of G. inflata Bat., which were available for the study, were not distinguished from G. glabra by this method. Our investigation revealed that five of the twenty-eight samples made a wrong label claim. The HPTLC results were confirmed by deoxyribonucleic acid (DNA) barcoding. For the quantitative analysis of the ma...
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