Abstract
BackgroundThe objective of this study was to clarify the association of quadriceps muscle strength with knee pain using a large-scale, population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study.MethodsFrom the 2566 subjects at the third visit of the ROAD study, the present study analyzed 2152 subjects who completed radiographic examinations and measurements of muscle strength and mass (690 men and 1462 women; mean age, 71.6 ± 12.2 years). Knee pain was assessed by an experienced orthopedist. Knee osteoarthritis (OA) was defined according to Kellgren-Lawrence (KL) grade. Quadriceps muscle strength and muscle mass at the lower limbs were measured by the Quadriceps Training Machine (QTM-05F, Alcare Co., Ltd. Tokyo, Japan) and the Body Composition Analyzer MC-190 (Tanita Corp., Tokyo, Japan), respectively.ResultsQuadriceps muscle strength and weight bearing index (WBI: quadriceps muscle strength by weight) were significantly associated with knee pain after adjustment for age and body mass index, whereas grip strength and muscle mass at the lower limbs were not. The significant association of quadriceps muscle strength with knee pain was independent of radiographic knee OA.ConclusionThe present cross-sectional study showed an independent association of quadriceps muscle strength with knee pain.Electronic supplementary materialThe online version of this article (doi:10.1186/s12891-015-0737-5) contains supplementary material, which is available to authorized users.
Highlights
The objective of this study was to clarify the association of quadriceps muscle strength with knee pain using a large-scale, population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study
To determine the prevalence of knee pain according to muscle strength, subjects were classified by muscle strength (
The present study first clarified that quadriceps muscle strength and weight bearing index (WBI) were significantly associated with knee pain even after adjustment for radiographic knee OA, which means that the association of muscle strength with knee pain is independent of radiographic changes
Summary
The objective of this study was to clarify the association of quadriceps muscle strength with knee pain using a large-scale, population-based cohort of the Research on Osteoarthritis/osteoporosis Against Disability (ROAD) study. Knee osteoarthritis (OA) is a major public health issue that causes chronic pain and disability [1,2,3]. According to the recent National Livelihood Survey of the Ministry of Health, Labour and Welfare in Japan, OA is ranked fourth among diseases that cause disabilities that subsequently require support with activities of daily living [6]. Much effort has been devoted toward a definition of knee pain, its correlation with radiographic severity of knee OA is not as strong as one would expect [4, 8,9,10].
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