Abstract

s / Osteoarthritis and Cartilage 21 (2013) S63–S312 S276 and 4.2% in the ECC RX, CONC RX and CON, respectively. The Functional subscores decreased by 31.0% (ECC RX), 34.7% (CONC RX) and 8% (CON). The changes in the NRSpain ratings reported by participants during chair rise and stair time tasks were not significantly different between groups by week 16. Pain decreased by 32% (CONC RX) and 52% (ECC RX) in chair rise and by 50% (CONC RX) and 34% (ECC RX). The CON group pain increased 30% in chair rise and decreased 35% in stair climb. Chair rise time, stair climb time and walking endurance were not different between groups over time. Daily steps were measured using a seven day StepWatch monitoring of ambulatory activity. The six minute walk distance did not significantly improve over time; but peak walking pain decreased from 2.9 to 1.5 points in CONC RX and from 1.7 to 1.1 points in ECC RX by week 16. There was a faster weekly program progression with CONC RX versus ECC RX in leg press and leg curl, but not leg extension exercise. Attrition rates were the same for the three groups (w33%). Adverse events were higher with ECC RX when compared to CONC RX and were related to musculoskeletal discomforts and pain (CONC RX1⁄42, ECC RX1⁄48). Conclusions: Both modes of RX improved physical function and leg strength in persons with knee OA. Due to the slower progression in the ECC RX program and potential for higher musculoskeletal discomforts, it may be recommended to use CONC RX until prescriptions for ECC RX are optimized for patient comfort. 538 GAIT AND CLINICAL IMPROVEMENT WITH A NOVEL KNEE BRACE FOR KNEE OA A. Bhave. Rubin Inst. of Advanced Orthopedics at Sinai Hosp., Baltimore,

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