QUAD: a computer package for the analysis of QUantal assay data

Abstract

The computer package QUAD has been developed at the University of Kent, U.K. It is menu-driven and written in Advanced BASIC. It runs on IBM PC compatible machines equiped with a suitable graphics facility such as CGA or simulated CGA. QUAD is available on a floppy disk, for a small handling charge. QUAD has four main functions: it performs a logit analysis of quantal assay data; it provides a flexible way of analysing the data, allowing dose transformations and providing alternative confidence intervals for ED p values; it produces a range diagnostics for assessing the fit of models to data; it provides and fits two families of extended models, each containing the logit as a special case. The package makes use of the latest statistical research, and fitted models are displayed by means of the good graphics facilities available on microcomputers. This document describes the facilities available in detail, and provides and discusses illustrations of the package at work. QUAD has been designed as a pilot package. Further additions and developments are planned and described later.