QT dispersion and left ventricular function after stent placement in acute myocardial infarction

Abstract

Background QT dispersion is increased in acute myocardial infarction (AMI), but the relation of QT dispersion to left ventricular (LV) function has not yet been fully elucidated. The purpose of this study was to evaluate the relationship between QT dispersion and LV function in patients with successful coronary stenting in AMI. Methods Seventy five patients with AMI who underwent percutaneous transluminal coronary angioplasty (PTCA) were enrolled in this study. Corrected QT dispersion was measured before, immediately after, 24 h after, 48 h after, and 6 months after PTCA. Left ventricular ejection fraction (LVEF) was evaluated by left ventriculography at 6 months after PTCA. Results Corrected QT dispersion at 24 h after and 48 h after PTCA were significantly related to LVEF by univariate analysis ( r = − 0.282, p < 0.05 and r = − 0.326, p < 0.01, respectively). In multiple regression model, corrected QT dispersion at 24 h after and 48 h after PTCA revealed significant associations with LVEF ( R 2 = 0.441, coefficient = − 0.283, p = 0.006 and R 2 = 0.411, coefficient = − 0.225, p = 0.039, respectively), but corrected QT dispersion before, immediately after, and 6 months after PTCA were not associated with LVEF. Conclusions Corrected QT dispersion at 24 h after and 48 h after PTCA in AMI correlate with LVEF at 6 months after PTCA.