Abstract
Introduction: Blood product transfusion may contribute to overall morbidity and mortality in the intensive care unit patient population. In lung transplants necessitating cardiopulmonary bypass (CPB), aprotinin has been shown to decrease transfusion requirements. More recently, off-pump transplantation has become the standard of care. The efficacy of aprotinin use in this population has yet to be definitively examined. We postulate that aprotinin use during off-pump bilateral orthotopic lung transplantation (OP-BOLT) reduces peri-operative transfusions.
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