Abstract

Non-invasive fetal electrocardiography (NI-FECG) plays an important role in fetal heart rate (FHR) measurement during the pregnancy. However, despite the large number of methods that have been proposed for adult ECG signal processing, the analysis of NI-FECG remains challenging and largely unexplored. In this study, we propose a prefix tree-based framework, called QRStree, for FHR measurement directly from the abdominal ECG (AECG). The procedure is composed of three stages: Firstly, a preprocessing stage is employed for noise elimination. Secondly, the proposed prefix tree-based method is used for fetal QRS complexes (FQRS) detection. Finally, a correction stage is applied for false positive and false negative correction. The novelty of the framework relies on using the range of FHR to establish the connections between the FQRS. The consecutive FQRS can be considered as strings composed of alphabet items, thus we can use the prefix tree to store them. A vertex of the tree contains an alphabet, thus a path of the tree gives a string. Such that, by storing the connections of the FQRS into the prefix tree structure, the problem of FQRS detection converts to a problem of optimal path selection. Specifically, after selecting the optimal path of the tree, the nodes in the optimal path are collected as detected FQRS. Since the prefix tree can cover every possible combination of the FQRS candidates, it has the potential to reduce the occurrence of miss detections. Results on two different databases show that the proposed method is effective in FHR measurement from single-channel AECG. The focus on single-channel FHR measurement facilitates the long-term monitoring for healthcare at home.

Highlights

  • Non-invasive fetal electrocardiography (NI-fetal ECG (FECG)) can be used for fetal heart rate (FHR) measurement throughout the pregnancy [1,2,3,4]

  • Unlike the template subtraction (TS) methods which are based on the elimination of maternal ECG (MECG), we propose a novel method to detect the location of fetal QRS complexes (FQRS) directly from the abdominal ECG (AECG)

  • The real AECG records from the PhysioNet/Computing in cardiology challenge database (PCDB) and ADFECGDB are collected to evaluate the efficiency of the proposed method

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Summary

Introduction

Non-invasive fetal electrocardiography (NI-FECG) can be used for fetal heart rate (FHR) measurement throughout the pregnancy [1,2,3,4]. Extracting the FHR information from the abdominal ECG (AECG) remains a challenging task [5,6,7]. The AECG collected from the abdomen is inevitably affected by a variety of noise interferences [8]. The maternal ECG (MECG) component of the AECG is the predominant interference source, which has a much larger amplitude than the fetal ECG (FECG) (see Fig 1) [9,10,11].

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