Qral and maxillofacial perspective of gorlin-goliz syndrome: A clinical case series of three patients

Abstract

Gorlin-Goltz syndrome is an autosomal dominant inherited syndrome. It is also known as hereditary cutaneo-mandibular polyonocosis, multiple nevoid basal cell epithelioma-jaw cysts or bifid rib syndrome. Clinical criteria required for the diagnosis of Gorlin-Goltz syndrome includes a positive family history of the syndrome, presence of basal cell carcinomas, jaw cysts, and palmoplantar pits. The aim is to present the diagnosis, clinical features, and management of Gorlin-Goltz syndrome. Presented here is case series of three males suffering from Gorlin-Goltzsyndrome, their clinical manifestations and management. In conclusion, oral and maxillofacial manifestations of GorlinGotz syndrome play an important role in the diagnosis, initiate early preventive treatment and provide genetic advice, hence a thoroughknowledge of the clinical management is important. Early diagnosis and management of Gorlin-Goltz syndrome are important to avoid complications associated with thesyndrome.