Abstract
BackgroundAutistic spectrum disorders are a group of neurological and developmental disorders associated with social, communication, sensory, behavioral and cognitive impairments, as well as restricted, repetitive patterns of behavior, activities, or interests.The aim of this study was a) to analyze QEEG findings of autistic patients and to compare the results with data base; and b) to introduce the calculation of spectrum weighted frequency (brain rate) as an indicator of general mental arousal in these patients.ResultsResults for Q-EEG shows generally increased delta-theta activity in frontal region of the brain. Changes in QEEG pattern appeared to be in a non-linear correlation with maturational processes.Brain rate measured in CZ shows slow brain activity (5. 86) which is significantly lower than normal and corresponds to low general mental arousal.Recent research has shown that autistic disorders have as their basis disturbances of neural connectivity. Neurofeedback seems capable of remediating such disturbances when these data are considered as part of treatment planning.ConclusionsPrognosis of this pervasive disorder depends on the intellectual abilities: the better intellectual functioning, the possibilities for life adaptation are higherQEEG shows generally increased delta-theta activity in frontal region of the brain which is related to poor cognitive abilities.Brain rate measured in CZ shows slow brain activity related to under arousal.Pharmacotherapy combined with behavior therapy, social support and especially neurofeedback technique promise slight improvements
Highlights
Autistic spectrum disorders are a group of neurological and developmental disorders associated with social, communication, sensory, behavioral and cognitive impairments, as well as restricted, repetitive patterns of behavior, activities, or interests
(2) Brain rate assessment In addition to the analysis of Quantitative electroencephalographic (QEEG) characteristics of autistic children we introduced the calculation of spectrum weighted frequency or brain rate as an indicator of general mental activity
We showed through obtained results that main characteristics of QEEG in autistic children are slowing of the brain activity which is statistically significant when comparing with the data base
Summary
Autistic spectrum disorders are a group of neurological and developmental disorders associated with social, communication, sensory, behavioral and cognitive impairments, as well as restricted, repetitive patterns of behavior, activities, or interests. Autistic spectrum disorders (ASD) include autism, pervasive developmental disorder and Asperger’s. These are life-changing, familyaltering conditions usually diagnosed in early childhood. In recent years, this group of impairment has shown a dramatic increase in prevalence, which raises the clinical. The broad variation in phenotypes and severities within autism spectrum disorders suggests the involvement of multiple predisposing factors, interacting in complex ways with normal developmental courses and gradients. Despite more than several decades of genetic study, the precise etiology of ASD still remains unknown, largely due to the genetic and phenotypic diversity, or heterogeneity of this disorder, and the lack of biologically based classification systems [8,9,10]
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