Year-end Sale % OFF 
Abstract
Although a relatively simple system, pyrrolo[1,2-b]pyridazines have been subject to numerous studies and synthetic attempts. The present review represents an update to the 1976 review of Kuhla and Lombardino.
Highlights
Pyrrolo[1,2-b]pyridazine 1 is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, formally obtained by the condensation of pyridazine and pyrrole
The synthesis and properties of the pyrrolo[1,2-b]pyridazines were reviewed in 1977 by Kuhla and Lombardino,[1] the high interest in the synthetic pathways leading to such derivatives and their properties has remained constant to this date
We present the approaches for the obtaining of the pyrrolo[1,2-b]pyridazine system and its uses reported after Kuhla and Lombardino’s review.[1]
Summary
Pyrrolo[1,2-b]pyridazine 1 is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, formally obtained by the condensation of pyridazine and pyrrole. The numbering of the atoms from the pyrrolo[1,2-b]pyridazine scaffold, known in literature as 5-azaindolizine, is presented in Formula 1. The synthesis and properties of the pyrrolo[1,2-b]pyridazines were reviewed in 1977 by Kuhla and Lombardino,[1] the high interest in the synthetic pathways leading to such derivatives and their properties has remained constant to this date. We present the approaches for the obtaining of the pyrrolo[1,2-b]pyridazine system and its uses reported after Kuhla and Lombardino’s review.[1] The same classification of the synthetic methods was used as in the first review, considering the starting compounds: syntheses starting from pyridazine and its derivatives, syntheses starting from the pyrrole ring and syntheses starting from acyclic compounds
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
