Abstract
Organocatalytic enantioselective Michael addition of α,α-disubstituted aldehydes onto nitroolefins using pyrrolidine–oxyimide catalyst was reported. The reaction works effectively under neat conditions with 15mol% of catalyst and 10mol% of p-nitrobenzoic acid as an additive at 0°C; this results in the formation of Michael adducts possessing an all-carbon quaternary center with good yields and enantioselectivities.
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