Abstract
Clinical manifestations, MRI abnormalities, learning disabilities, and effect of pyridoxine dose on intelligence quotients were studied in 6 definite and 3 possible cases of pyridoxine dependent seizures in children, ages 2.5 to 14 years, seen at Newcastle General Hospital, Newcastle upon Tyne, UK.
Highlights
Clinical manifestations, MRI abnormalities, learning disabilities, and effect of pyridoxine dose on intelligence quotients were studied in 6 definite and 3 possible cases of pyridoxine dependent seizures in children, ages 2.5 to 14 years, seen at Newcastle General Hospital, Newcastle upon Tyne, UK
Zinc deprivation caused a progressive decrease in daytime activity levels and impaired attention followed by growth retardation
Motor activity levels and attention may be decreased during early stages of zinc deprivation and before the onset of growth retardation
Summary
MRI abnormalities, learning disabilities, and effect of pyridoxine dose on intelligence quotients were studied in 6 definite and 3 possible cases of pyridoxine dependent seizures in children, ages 2.5 to 14 years, seen at Newcastle General Hospital, Newcastle upon Tyne, UK. Compared to an adequate zinc intake (50 mcg/gm) were compared using 24hour activity patterns and an attention task performance in 10 adolescent female monkeys (18-33 months of age) at the California Regional Primate Research Center, University of California, Davis, CA. Zinc deprivation caused a progressive decrease in daytime activity levels and impaired attention followed by growth retardation. Activity and attention in zinc-deprived adolescent monkeys.
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