Pyrazoles as Building Blocks in Heterocyclic Synthesis: Synthesis of Some New Substituted 1‐Triazinylpyrazolo[3,4‐d]pyrimidine and 1‐Triazinylpyrazolo[3,4‐b]pyridine Derivatives.

Abstract

Several new pyrazolo[3,4-d]pyrimidines and pyrazolo[3,4-b]pyridine derivatives were prepared by condensation of 5-amino-1-(5,6-diphenyl-1,2,4-triazin-3-yl)-1H-pyrazole-4-carbonitrile with succinic anhydride, acetic anhydride, γ-chlorobutyl chloride, succinyl chloride, formic acid—formamide mixture, formamide, and active methylene reagents such as malononitrile, ethyl cyanoacetate, and ethyl acetoacetate under different reaction conditions.