Abstract
Infections are among the most common complications transplant physicians face when dealing with solid organ transplant recipients. We present a case of pyomyositis caused by Staphylococcus aureus in a patient with IgA nephropathy and a kidney transplant, under treatment with mTOR inhibitors and prednisone. This entity is a rare intramuscular infection, given the resistance of healthy muscle to colonization. We review the most frequent agents, the diagnostic algorithm, and therapeutic alternatives. We also comment on the role of mTOR inhibitors in this case as possible predisposing factor for the infection.
Highlights
Pyomyositis is a rare intramuscular bacterial infection, given the resistance of healthy muscle to colonization
The true incidence of pyomyositis is unknown since it is an underreported disease [1]
It usually occurs in the context of muscle injury, surgery, or ischemia, or when the host’s defense mechanisms are compromised, such as in immunosuppressed patients, diabetes mellitus, renal insufficiency, liver disease, AIDS with low CD4+ lymphocytes count, or use of intravenous drugs [2]
Summary
Pyomyositis is a rare intramuscular bacterial infection, given the resistance of healthy muscle to colonization. It presents initially as muscular inflammation, generally of subacute onset, and it later progresses to form abscesses. It may have atypical presentations that could delay its diagnosis or underestimate the signs of severity. We here present a case of pyomyositis in an immunosuppressed kidney transplant recipient
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