Abstract
Summary.— A patient with severe pyoderma gangrenosum, without any other associated conditions, is reported. She was found to present 2 major abnormalities of cellular immunity, i.e. lack of lymphocyte cytotoxicity induced by phytohaemagglutinin and failure of dinitrofluorobenzene sensitization. Intra dermal reactions to tuberculin, trichophytin and candidin were negative, while intradermal injections of streptoccal antigen twice provoked large ulcers at the sites of injection. Dermonecrotic factor was present in her serum. High doses of steroids had to be given to heal her ulcers. Copyright © 1972, Wiley Blackwell. All rights reserved
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