Pyoderma Gangrenosum in Inflammatory Bowel Disease: A Rare Case Involving Mandibular, Elbow, and Pubic Ulcers

Abstract

Pyoderma gangrenosum (PG) is a rare, inflammatory skin condition primarily characterized by painful ulcers with undermined borders, commonly occurring on the lower extremities. In approximately fifty percent of cases, PG is associated with underlying systemic diseases, including inflammatory bowel disease (IBD), inflammatory arthritis, or myeloproliferative disorders. PG is notorious for its variable clinical manifestations, which can closely resemble other dermatological conditions, often leading to misdiagnosis and inappropriate treatment. This case underscores the importance of including PG in the differential diagnosis for patients with ulcerative skin lesions to ensure prompt diagnosis and treatment. Furthermore, it highlights the necessity of screening for IBD in patients diagnosed with PG.