Abstract

Introduction Double balloon enteroscopy (DBE) is a relatively invasive and lengthy procedure necessitating careful consideration of patients’ comorbidities. We aim to assess the safety of DBE in patients with cardiovascular disease (CVD). Methods Between June 2006 and January 2016, 568 consecutive patients undergoing DBE were reviewed across 3 teaching hospitals in the UK and Italy. Demographic and clinical data were collected and patients were categorised by age (elderly: ≥70 years and young: Results CVD was present in 185 patients (mean age 70±9.7, 51% male) who underwent DBE for iron deficiency anaemia (54%) overt gastrointestinal bleeding (25%), suspected Crohn’s disease (10%), small bowel strictures (6%) and suspected coeliac disease complications (4%). CVD (elderly vs young) included ischaemic heart disease (59% vs 68%, p = 0.2), valve replacement (23% vs 16%, p = 0.3), atrial fibrillation (31% vs 11%, p All CVD patients were compared to 383 patients without CVD (mean age 50±14.1, 44% male). Diagnostic yield was higher in those with CVD compared to those without (65% vs 50%, p Conclusion We report the first multicentre study attesting the safety of patients with CVD undergoing DBE. Moreover, patients with CVD have higher diagnostic and therapeutic yield at DBE and thus with careful selection, these patients are most likely to benefit from the procedure. Disclosure of Interest None Declared

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