PW047 Echocardiography Underestimates Maximum Interventricular Septum Thickness in Hypertrophic Cardiomyopathy

Abstract

Introduction: Takotsubo cardiomyopathy (TC) is characterized by a transient left ventricular (LV) dysfunction, but the prognosis of TC is not yet fully established. Objectives: Toevaluate in-hospital andmediumtermprognosis of patientsdiagnosedwithTC. Methods: Multicenter study involving 5 hospital centers that included all patients diagnosed with TC in the last 10 years. Results: We included 71patients with TC, predominantly females (91.5%). Mean age was 67 11 years. Chest pain was the most common clinical presentation (93%). Emotional or physical stress was identified as a possible triggering factor in 60.6% of patients. The admission ECG showed ST-segment elevation (56.3%) or depression (32.4%) in most patients. There was elevation of troponin I on admission in 83.1% of cases (peak value of 4.2 4.3ng/mL). Echocardiogram revealed akinesia of apical and medium LV segments in 97.2% of cases. The coronary angiography revealed no coronary disease(85.9%).During hospitalization (6.1 4.6 days) occurred complications: heart failure (31%), cardiogenic shock (15.5%), atrial fibrillation (9.9%), complete atrioventricular block (4.2 %), acute pulmonary edema (4.2%), stroke / TIA (2.8%), LV thrombus (1.4%) and death (1.4%). Complete reversal of LV dysfunction occurred in 38% during hospitalization and in 43.7% up to 15 days after admission. Over a follow-up of 31 29 months, there were: TC recurrence (4.2%), stroke / TIA (4.2%) and death (1.4%). Conclusion: In the acute phase, TC has a high prevalence of complications, particularly heart failure and cardiogenic shock, and severe complications such as stroke and death may also occur. At the medium term follow-up, the prognosis is good with a low prevalence of stroke / TIA, a low mortality and a low recurrence rate. Disclosure of Interest: None Declared