Abstract
Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia. This cluster of syndromes became known as Sweet’s syndrome. There have been many published cases in children of neutrophilic dermatoses and fever which are labeled as Sweet’s syndrome. Recently, however, neutrophilic dermatoses have been associated with some autoimmune and autoinflammatory diseases .
Highlights
Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia
Patient 3 is a child with panniculitis raised inflammatory markers, arthritis and lipodystrophy
She presented with hepatitis, myositis, nephritis and macrophage activation syndrome. She was diagnosed with chronic atypical neutrophilic dermatosis, lipodystrophy and elevated temperature (CANDLE) syndrome, a recently described autoinflammatory condition
Summary
Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia. PW03-022 – Neutrophilic skin disease and inflammation From 7th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID) Lausanne, Switerland. Introduction Robert Sweet first described a syndrome with a painful, erythematous nodular plaques, neutrophilic dermal infiltrates, fevers and peripheral neutrophilia.
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