Abstract
Familial Mediterranean Fever (FMF) is an ethnic disease for Armenian population and represents a significant health care problem. Frequency of carriers of MEFV mutations is 1:3, and the prevalence of FMF is rather high (14-100:10000). During the period between 2003 and 2012 there was a 4.5-fold increase of the total number of children with FMF. Many of these cases have severe clinical picture and atypical course, which may complicate timely diagnosis.
Highlights
Familial Mediterranean Fever (FMF) is an ethnic disease for Armenian population and represents a significant health care problem
FMF manifestation during the first decade of life were determined in 95.2% of patients
FMF onset before 5 years was in 78.6%
Summary
To establish phenotype-genotype correlations in Armenian children with FMF
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