Abstract
We report 3 cases of Puumala virus infection in a family in Switzerland in January 2019. Clinical manifestations of the infection ranged from mild influenza-like illness to fatal disease. This cluster illustrates the wide range of clinical manifestations of Old World hantavirus infections and the challenge of diagnosing travel-related hemorrhagic fevers.
Highlights
World hantaviruses ranges from 1%–10% for Dobrava-Belgrade and Hantaan orthohantaviruses to
Most cases occur in Western Russia and are caused by PUUV and Dobrava-Belgrade orthohantaviruses (2)
In Switzerland, local acquisition of PUUV is rare (6). This familial cluster highlights the wide spectrum of clinical manifestations of PUUV, which can range from an influenza-like illness to the classical nephropathy to a rapidly fatal hemorrhagic fever with shock and multiple organ failure
Summary
World hantaviruses ranges from 1%–10% for Dobrava-Belgrade and Hantaan orthohantaviruses to
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