Abstract
The occurrence of purple glove syndrome following the inadvertent oral administration of 1000 mg phenytoin/day is reported in a 10-year-old 18 kg handicapped boy who was admitted in coma to the Niigata City General Hospital, Japan.
Highlights
The occurrence of purple glove syndrome following the inadvertent oral administration of 1000 mg phenytoin/day is reported in a 10-year-old 18 kg handicapped boy who was admitted in coma to the Niigata City General Hospital, Japan
Purple glove syndrome caused by oral administration of phenytoin
This appears to be the first report of the syndrome associated with oral phenytoin, administered in an overdose (55 mg/kg/d)
Summary
The occurrence of purple glove syndrome following the inadvertent oral administration of 1000 mg phenytoin/day is reported in a 10-year-old 18 kg handicapped boy who was admitted in coma to the Niigata City General Hospital, Japan. Shuddering attacks (SA) are an uncommon benign disorder of infants and young children, with movements resembling shivering and straining, without impaired consciousness or epileptiform EEG, and showing resolution or improvement by 2 or 3 years of age. One previous report considered SAs an early manifestation of essential tremor (Vanasse M et al Neurology 1976;26:1027-30). Infantile tremor syndrome due to magnesium nutritional deficiency (Meningoencephalitic syndrome) should be considered in differential diagnosis.
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