Purity Determination of Fusidic Acid Using Physico-chemical Methods

Abstract

When a new drug product is prefomulated and later is accepted as a future commercial product is important to test stability and also higher purity of medical substances which should be processed during drug production. In present paper was checked the purity of fusidic acid, a relatively new antibiotic acting on gram positive bacteria, and is used as treatment for acne vulgaris. Purity and also thermal stability of this new class of antibiotics was tested using physicochemical test methods, such as: Fourier transform Infrared Spectroscopy (FTIR), XRay Diffraction (XRD), Scanning Electron Microscopy (SEM), and also Thermal Analysis.