Abstract
1. 1. The pathways of purine ribonucleotide synthesis and interconversion that are operative in the gravid rat lung worm, Angiostrongylus cantonensis, were identified by radioisotope tracing in intact whole worms and by measurement of enzyme activities in cell-free extracts 2. 2. Ribonucleotides were rapidly formed by utilization of adenine, hypoxanthine and guanine and by direct phosphorylation of adenosine. 3. 3. AMP and GMP were interconvertible but these reactions were very slow. 4. 4. The synthetic capacities of purine ribonucleotide metabolism were much higher than the catabolic functions in the parasite at this particular stage of the life cycle.
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